Ulwazi oluyisisekelo
1. Isigaba I-syphilitic chancre eqinile kufanele ihlukaniswe ne-chancre, ukuqhuma kwezidakamizwa okungaguquki, i-herpes yobulili, njll.
2. Ukwandiswa kwe-lymph node okubangelwa i-chancre ne-venereal lymphogranuloma kufanele kuhlukaniswe kulokho okubangelwa ugcunsula oyinhloko.
3. Ukuqubuka kwe-syphilis yesibili kufanele kuhluke ku-pityriasis rosea, i-erythema multiforme, i-tinea versicolor, i-psoriasis, i-tinea corporis, njll. I-Condyloma planum kufanele ihlukaniswe ne-condyloma acuminatum.
Ukutholwa kwe-Treponema pallidum IgM antibody
Igama Lomkhiqizo | Ikhathalogi | Uhlobo | Umsingathi/Umthombo | Ukusetshenziswa | Izinhlelo zokusebenza | I-Epitope | I-COA |
I-TP Fusion Antigen | I-BMTP103 | I-Antigen | E.coli | Thwebula | CMIA, WB | Amaprotheni 15, Amaprotheni17, Amaprotheni47 | Landa |
I-TP Fusion Antigen | I-BMTP104 | I-Antigen | E.coli | Hlanganisa | CMIA, WB | Amaprotheni 15, Amaprotheni17, Amaprotheni47 | Landa |
Ngemva kokutheleleka nge-syphilis, i-antibody ye-IgM ivela kuqala.Ngokukhula kwalesi sifo, i-antibody ye-IgG ivela kamuva futhi ikhuphuka kancane.Ngemva kokwelashwa okuphumelelayo, i-antibody ye-IgM yanyamalala futhi amasosha omzimba e-IgG aphikelela.I-antibody ye-TP IgM ayikwazi ukudlula ku-placenta.Uma usana lune-TP IgM positive, kusho ukuthi usana lunegciwane.Ngakho-ke, ukutholwa kwe-TP IgM antibody kubaluleke kakhulu ekuxilongeni ugcunsula wengane ezinsaneni.