I-HEV(Ishesha)

I-Hepatitis E (i-Hepatitis E) yisifo esithathelwanayo esiyingozi esisakazwa yindle.Selokhu kwagqashuka isifo sokusha kwesibindi kohlobo E sokuqala eNdiya ngo-1955 ngenxa yokungcoliswa kwamanzi, sesidlangile eNdiya, Nepal, Sudan, Kyrgyzstan of the Soviet Union, Xinjiang nakwezinye izindawo eChina.

I-HEV ikhishwa ngendle yeziguli, isatshalaliswa ngokuthintana kwansuku zonke, futhi ingasatshalaliswa noma kuqubuke ubhubhane olubangelwa ukudla okungcolile nemithombo yamanzi.Isilinganiso esiphezulu sezigameko ngokuvamile sisenkathini yemvula noma ngemva kwezikhukhula.Isikhathi se-incubation singamaviki angu-2 ~ 11, kanye nesilinganiso samaviki ayisi-6.Iningi leziguli zasemtholampilo zinesifo sokusha kwesibindi esimaphakathi kuya komaphakathi, esivame ukuzikhawulela, futhi asithuthuki sibe yi-HEV engapheli.Ihlasela kakhulu abantu abasha, abangaphezu kuka-65% abaneminyaka yobudala ephakathi kwe-16 kuya kweyi-19 ubudala, futhi izingane zinezifo eziningi ezingaphansi komtholampilo.

Izinga lokufa kwabantu abadala liphezulu kunelesifo sokusha kwesibindi kohlobo A, ikakhulukazi kwabesifazane abakhulelwe abaphethwe yisifo sokusha kwesibindi kohlobo E, kanti izinga lokufa kwabantu abangenwe yileli gciwane ezinyangeni ezintathu ezedlule lingama-20%.
Ngemuva kokutheleleka nge-HEV, ingakhiqiza ukuvikeleka kwamasosha omzimba ukuze kuvikelwe i-HEV yokutheleleka kabusha kohlobo olufanayo noma uhlobo oluhlukile.Kubikwa ukuthi i-anti-HEV antibody ku-serum yeziguli eziningi ngemva kokuvuselelwa ihlala iminyaka engu-4-14.
Ukuze kuhlolwe ukuhlolwa, izinhlayiya zegciwane zingatholakala endle ngesibonakhulu se-electron, i-HEV RNA enyongweni ye-fecal ingatholwa yi-RT-PCR, futhi amasosha omzimba e-anti HEV IgM kanye ne-IgG ku-serum angatholwa yi-ELISA esebenzisa i-HEV glutathione S-transferase fusion protein njenge-antigen.
Ukuvimbela okuvamile kwe-hepatitis E kuyafana nalokho kwe-hepatitis B. Ama-immunoglobulins avamile awasebenzi ekugomeni okuphuthumayo okuphuthumayo.