Incazelo enemininingwane
I-Hepatitis A ibangelwa igciwane le-hepatitis A (HAV) futhi isakazwa kakhulu ngomzila we-fecal-oral, ikakhulukazi ezigulini.Isikhathi sokushiswa kwesifo sokusha kwesibindi kohlobo A siyizinsuku ezingu-15–45, futhi igciwane livame ukuba khona egazini lesiguli nasendle ezinsukwini ezingu-5–6 ngaphambi kokuba i-transcarbidine iphakanyiswe.Ngemuva kwamaviki angu-2-3 okuqala, ngokukhiqizwa kwamasosha omzimba athile ku-serum, ukutheleleka kwegazi kanye nendle kuyanyamalala kancane kancane.Ngesikhathi sokutheleleka okusobala noma okulumba kwe-hepatitis A, umzimba ungakhiqiza amasosha omzimba.Kunezinhlobo ezimbili zamasosha omzimba (anti-HAV) ku-serum, i-anti-HAVIgM ne-anti-HAVIgG.I-Anti-HAVIgM ibonakala kusenesikhathi, ngokuvamile ibonakala ezinsukwini ezimbalwa iqalile, futhi isikhathi se-jaundice sifinyelela umvuthwandaba, okuyinkomba ebalulekile yokuhlonza ngokushesha i-hepatitis A. I-Anti-HAVIgG ibonakala sekwephuzile futhi ihlala isikhathi eside, ngokuvamile ingalungile esigabeni sokuqala sokutheleleka, futhi i-anti-HAVIgG positive ikhombisa ukutheleleka kwe-HAV yangaphambilini futhi ivame ukusetshenziswa ekuphenyweni kwe-epidemiological.Ukuhlolwa kwe-microbiological ye-hepatitis A kusekelwe ikakhulukazi kuma-antigen kanye namasosha omzimba wegciwane le-hepatitis A.Izindlela zokufaka isicelo zifaka i-immunoelectron microscopy, ukuhlolwa okubophayo okuhambisanayo, ukuhlolwa kwe-immunoadhesion hemagglutination, i-solid-phase radioimmunoassay kanye ne-enzyme-linked immunosorbent assay, i-polymerase chain reaction, ubuchwepheshe be-cDNA-RNA molecular hybridization, njll.