Incazelo enemininingwane
I-Chlamydia pneumoniae (C. pneumoniae) iwuhlobo olujwayelekile lwebhaktheriya futhi iyimbangela enkulu yenyumoniya emhlabeni jikelele.Cishe u-50% wabantu abadala unobufakazi bokuthi bangenwe yilesi sifo ngesikhathi beneminyaka engama-20, futhi ukuphinda batheleleke kamuva ekuphileni kuvamile.Ucwaningo oluningi luye lwaphakamisa ukuhlobana okuqondile phakathi kokutheleleka kwe-C. pneumoniae nezinye izifo ezivuvukalayo njenge-atherosclerosis, ukukhushulwa okunamandla kwe-COPD, nesifo somoya.Ukuxilonga ukutheleleka kwe-C. pneumoniae kuyinselele ngenxa yemvelo esheshayo ye-pathogen, ukutholakala kwe-seroprevalence enkulu, kanye nethuba lokuhamba kwesikhashana okungabonakali.Izindlela zaselabhorethri zokuxilonga ezimisiwe zifaka ukuhlukaniswa kwento ephilayo kusiko lamaseli, ama-serological assays kanye ne-PCR.Ukuhlolwa kwe-Microimmunofluorescence (MIF), "izinga legolide" lamanje lokuxilongwa kwe-serological, kodwa ukulinganisa kusantula ukumiswa futhi kuyinselele ngokobuchwepheshe.Ama-antibody immunoassay ukuhlola okujwayelekile kwe-serology okusetshenziswayo futhi ukutheleleka kwe-chlamydial okuyinhloko kubonakala ngokusabela okuvelele kwe-IgM phakathi kwamaviki ama-2 kuya kwangu-4 kanye nokulibaziseka kwe-IgG ne-IgA phakathi kwamaviki angu-6 kuya kwangu-8.Kodwa-ke, ekuthelelekeni kabusha, amazinga e-IgG ne-IgA akhuphuka ngokushesha, ngokuvamile emasontweni angu-1-2 kuyilapho amazinga e-IgM engase angabonakali.Ngenxa yalesi sizathu, amasosha omzimba e-IgA abonise ukuthi awuphawu oluthembekile lwe-immunological lwezifo eziyinhloko, ezingelapheki neziphindelelayo ikakhulukazi uma kuhlanganiswa nokutholwa kwe-IgM.